GW 627368
Catalog No: 91003
CAS Number: 439288-66-1
Purity: 98%
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 M. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 M.
For research use only. We do not sell to patients.
Chemical Information
| Name | GW 627368 |
|---|---|
| Synonyms | 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide |
| Molecular Formula | C30H28N2O6S |
| Molecular Weight | 544.6 |
| Smile | CCOc1c2ccccc2c(c3c1CN(C3=O)c4ccc(cc4)CC(=O)NS(=O)(=O)c5ccccc5)OCC |
| InChiKey | XREWXJVMYAXCJV-UHFFFAOYSA-N |
| InChi | InChI=1S/C30H28N2O6S/c1-3-37-28-23-12-8-9-13-24(23)29(38-4-2)27-25(28)19-32(30(27)34)21-16-14-20(15-17-21)18-26(33)31-39(35,36)22-10-6-5-7-11-22/h5-17H,3-4,18-19H2,1-2H3,(H,31,33) |
| CAS Number | 439288-66-1 |
| MDL | MFCD12912327 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Crystalline Solid |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
