GSK 2656157
Catalog No: 52019
CAS Number: 1337532-29-2
Purity: 98%
GSK2656157 is an ATP-competitive and highly selective inhibitor of PERK with IC50 of 0.9 nM, 500-fold greater against a panel of 300 kinases.
For research use only. We do not sell to patients.
Chemical Information
| Name | GSK 2656157 |
|---|---|
| Iupac Chemical Name | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone |
| Synonyms | GSK2656157 ; GSK 2656157 ; GSK-2656157 . |
| Molecular Formula | C23H21FN6O |
| Molecular Weight | 416.45 |
| Smile | NC=1C2=C(N=CN1)N(C=C2C=2C(=C1CCN(C1=CC2)C(CC2=NC(=CC=C2)C)=O)F)C |
| InChiKey | PRWSIEBRGXYXAJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,27) |
| CAS Number | 1337532-29-2 |
| Related CAS | 1337532-29-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | PERK Inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
