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GSK180736A (GSK180736)

Catalog No: 178901
CAS Number: 817194-38-0
Purity: 98.0% 

GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 M25 and >100-fold selectivity over other GRKs.  

For research use only. We do not sell to patients.

Chemical Information

NameGSK180736A (GSK180736)
Iupac Chemical Name4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 
SynonymsGSK180736A;GSK-180736A;GSK 180736A 
Molecular FormulaC19H16FN5O2 
Molecular Weight365.3684 
SmileFC1=CC=C(C=C1)C1NC(NC(=C1C(=O)NC=1C=C2C=NNC2=CC1)C)=O
InChiKeyHEAIGWIZTYAQTC-UHFFFAOYSA-N
InChiInChI=1S/C19H16FN5O2/c1-10-16(17(24-19(27)22-10)11-2-4-13(20)5-3-11)18(26)23-14-6-7-15-12(8-14)9-21-25-15/h2-9,17H,1H3,(H,21,25)(H,23,26)(H2,22,24,27)
CAS Number817194-38-0
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

178901 - GSK180736A (GSK180736) | CAS 817194-38-0

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