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GSK180736A (GSK180736)

Catalog No.: 178901
Cas No.: 817194-38-0
Purity : 98.0% 
178901 - GSK180736A (GSK180736) | CAS 817194-38-0

Catalog number : 178901

CAS number : 817194-38-0

Molecular Formula : C19H16FN5O2 

Molecular Weight : 365.3684 

Iupac Chemical Name : 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 

Smile : FC1=CC=C(C=C1)C1NC(NC(=C1C(=O)NC=1C=C2C=NNC2=CC1)C)=O

InChiKey : HEAIGWIZTYAQTC-UHFFFAOYSA-N

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SynonymsGSK180736A;GSK-180736A;GSK 180736A 
Molecular FormulaC19H16FN5O2 
Molecular Weight365.3684 
Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileFC1=CC=C(C=C1)C1NC(NC(=C1C(=O)NC=1C=C2C=NNC2=CC1)C)=O
InChiKeyHEAIGWIZTYAQTC-UHFFFAOYSA-N
InChiInChI=1S/C19H16FN5O2/c1-10-16(17(24-19(27)22-10)11-2-4-13(20)5-3-11)18(26)23-14-6-7-15-12(8-14)9-21-25-15/h2-9,17H,1H3,(H,21,25)(H,23,26)(H2,22,24,27)
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GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 M25 and >100-fold selectivity over other GRKs.  

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