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GRA Ex-25

Catalog No.: 17030701
Cas No.: 307983-31-9
Purity : 98% 
17030701 - GRA Ex-25 | CAS 307983-31-9

Catalog number : 17030701

CAS number : 307983-31-9

Molecular Formula : C29H36F3N3O5 

Molecular Weight : 563.6182 

Iupac Chemical Name : 3-(4-((1-(4-(tert-butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid 

Smile : C(C)(C)(C)C1CCC(CC1)N(C(=O)NC1=CC=C(C=C1)OC(F)(F)F)CC1=CC=C(C(=O)NCCC(=O)O)C=C1

InChiKey : BZXMLCVDKDXRQY-UHFFFAOYSA-N

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SynonymsGRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25 
Molecular FormulaC29H36F3N3O5 
Molecular Weight563.6182 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileC(C)(C)(C)C1CCC(CC1)N(C(=O)NC1=CC=C(C=C1)OC(F)(F)F)CC1=CC=C(C(=O)NCCC(=O)O)C=C1
InChiKeyBZXMLCVDKDXRQY-UHFFFAOYSA-N
InChiInChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)
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GRA Ex-25 is an inhibitor of glucagon receptor. Inhibiting the interaction between glucagon and its receptor has been reported to control hepatic glucose overproduction and thus GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus. 

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