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GNE-9605

Catalog No: 192284
CAS Number: 1536200-31-3
Purity: >98%

GNE-9605 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors.

For research use only. We do not sell to patients.

Chemical Information

NameGNE-9605
Iupac Chemical NameN2-(5-chloro-1-((3R,4R)-3-fluoro-1-(oxetan-3-yl)piperidin-4-yl)-1H-pyrazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine.
SynonymsGNE9605; GNE-9605; GNE 9605.
Molecular FormulaC17H20ClF4N7O
Molecular Weight449.83
SmileFC(C1=CN=C(NC2=C(Cl)N([C@H]3[C@H](F)CN(C4COC4)CC3)N=C2)N=C1NC)(F)F
InChiKeyPUXPEQJKNAWNQA-DGCLKSJQSA-N
InChiInChI=1S/C17H20ClF4N7O/c1-23-15-10(17(20,21)22)4-24-16(27-15)26-12-5-25-29(14(12)18)13-2-3-28(6-11(13)19)9-7-30-8-9/h4-5,9,11,13H,2-3,6-8H2,1H3,(H2,23,24,26,27)/t11-,13-/m1/s1
CAS Number1536200-31-3
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

192284 - GNE-9605 | CAS 1536200-31-3

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