GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of 1.2 nM.
For research use only. We do not sell to patients.
| Name | GDC-0575 |
|---|---|
| Iupac Chemical Name | (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide |
| Synonyms | GDC0575 (ARRY-575,RG7441);Cyclopropanecarboxamide, N-[4-[(3R)-3-amino-1-piperidinyl]-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]-;EOS-61380;ARRY-575;ARRY-575, RG7741;GDC-0575 (ARRY-575, RG7741) |
| Molecular Formula | C16H20BrN5O |
| Molecular Weight | 378.27 |
| InChiKey | |
| InChi | |
| CAS Number | 1196541-47-5 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |