GDC-0575 (ARRY-575, RG7741)是一种有效的选择性CHK1抑制剂,IC50为1.2 nM。
For research use only. We do not sell to patients.
Name | GDC-0575 |
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Iupac Chemical Name | (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide |
Synonyms | CYCLOPROPANECARBOXAMIDE, N-[4-[(3R)-3-AMINO-1-PIPERIDINYL]-5-BROMO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL] |
Molecular Formula | C16H20BrN5O |
Molecular Weight | 378.27 |
InChiKey | |
InChi | |
CAS Number | 1196541-47-5 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | 类白色至白色固体 |
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Purity | >98% |
Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
Solubility | 可溶于DMSO |
Handling | |
Shipping Condition | 可在常温下运输 |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |