Fulacimstat
Catalog No: 2071514
CAS Number: 1488354-15-9
Purity: 98% Min.
Fulacimstat, also known as BAY1142524, is a chymase inhibitor and antifibrotic drug candidate with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively. The orally available chymase inhibitor BAY 1142524 is currently being developed as a first-in-class treatment for left-ventricular dysfunction after myocardial infarction.
For research use only. We do not sell to patients.
Chemical Information
| Name | Fulacimstat |
|---|---|
| Iupac Chemical Name | 1-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)- 2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden- 1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid |
| Synonyms | Fulacimstat; BAY1142524; BAY-1142524; BAY 1142524; |
| Molecular Formula | C23H16F3N3O6 |
| Molecular Weight | 487.39 |
| Smile | O=C(C1=CN(C2=CC=C3N(C)C(OC3=C2)=O)C(N([C@@H]4CCC5=C4C=CC=C5C(F)(F)F)C1=O)=O)O |
| InChiKey | JDARDSVOVYVQST-MRXNPFEDSA-N |
| InChi | InChI=1S/C23H16F3N3O6/c1-27-17-7-5-11(9-18(17)35-22(27)34)28-10-14(20(31)32)19(30)29(21(28)33)16-8-6-12-13(16)3-2-4-15(12)23(24,25)26/h2-5,7,9-10,16H,6,8H2,1H3,(H,31,32)/t16-/m1/s1 |
| CAS Number | 1488354-15-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
