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Flavopiridol ( Alvocidib )

Catalog No: 237071
CAS Number: 146426-40-6
Purity: ≧98.0%

Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. It has a role as an antineoplastic agent, an EC (cyclin-dependent kinase) inhibitor, an antirheumatic drug and an apoptosis inducer. It is a dihydroxyflavone, a hydroxypiperidine, a member of monochlorobenzenes and a tertiary amino compound. It is a conjugate base of an alvocidib(1+).

For research use only. We do not sell to patients.

Chemical Information

NameFlavopiridol ( Alvocidib )
Iupac Chemical Name2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
Synonyms L 86-8275 ; L-868275 ; L 868275 ; L868275 ; HMR 1274 ; HMR-1274 ; HMR1274 ; Flavoperidol ; Alvocidib ;
Molecular FormulaC21H20ClNO5
Molecular Weight401.84
CAS Number146426-40-6
Related CAS146426-40-6

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationYellow solid
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
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Cell study
Animal study
Clinical study
Not available

Chemical Structure

237071 - Flavopiridol ( Alvocidib ) | CAS 146426-40-6

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