+86-27-65522453 sales@sun-shinechem.com

Firategrast

Catalog No.: 16122946
Cas No.: 402567-16-2
Purity : 98% 
16122946 - Firategrast | CAS 402567-16-2

Catalog number : 16122946

CAS number : 402567-16-2

Molecular Formula : C27H27F2NO6 

Molecular Weight : 499.5108 

Iupac Chemical Name : Firategrast 

Smile : CCOCc1cc(c(c(c1)OC)c2ccc(cc2)C[C@@H](C(=O)O)NC(=O)c3c(cccc3F)F)OC

InChiKey : YLFZHHDVRSYTKT-NRFANRHFSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsSB-683699; SB 683699; SB683699; T-0047; T 0047; T0047 
Molecular FormulaC27H27F2NO6 
Molecular Weight499.5108 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCCOCc1cc(c(c(c1)OC)c2ccc(cc2)C[C@@H](C(=O)O)NC(=O)c3c(cccc3F)F)OC
InChiKeyYLFZHHDVRSYTKT-NRFANRHFSA-N
InChiInChI=1S/C27H27F2NO6/c1-4-36-15-17-13-22(34-2)24(23(14-17)35-3)18-10-8-16(9-11-18)12-21(27(32)33)30-26(31)25-19(28)6-5-7-20(25)29/h5-11,13-14,21H,4,12,15H2,1-3H3,(H,30,31)(H,32,33)/t21-/m0/s1
MDLMFCD19443754
Coming soon.
Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). This could decrease multiple sclerosis (MS) activity, but may compromise CNS immune surveillance. The integrins are a sort of transmembrane receptors that modulate the signal transduction from ECM to the cell. They are associated with a lot of diseases such as cancer, inflammation and thrombotic diseases. 

402567-16-2 - Request Bulk Quote

×
402567-16-2 - Request Bulk Quote
Change