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FR 180204

Catalog No.: 52727
Cas No.: 865362-74-9
Purity : 98% 
52727 - FR 180204 | CAS 865362-74-9

Catalog number : 52727

CAS number : 865362-74-9

Molecular Formula : C18H13N7 

Molecular Weight : 327.34 

Chemical Name : FR 180204

Smile : c1ccc(cc1)c2c(c3ccccn3n2)c4cc5c(n[nH]c5nn4)N

InChiKey : XVECMUKVOMUNLE-UHFFFAOYSA-N

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Molecular FormulaC18H13N7 
Molecular Weight327.34 
Purity98% 
SolubilityDMSO 
Smilec1ccc(cc1)c2c(c3ccccn3n2)c4cc5c(n[nH]c5nn4)N
InChiKeyXVECMUKVOMUNLE-UHFFFAOYSA-N
InChiInChI=1S/C18H13N7/c19-17-12-10-13(20-22-18(12)23-21-17)15-14-8-4-5-9-25(14)24-16(15)11-6-2-1-3-7-11/h1-10H,(H3,19,21,22,23)
MDLMFCD14585805
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FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 M in enzymatic assays against ERK1 and ERK2, respectively. 

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