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FLLL32

Catalog No.: 16122709
Cas No.: 1226895-15-3
Purity : 98% 
16122709 - FLLL32 | CAS 1226895-15-3

Catalog number : 16122709

CAS number : 1226895-15-3

Molecular Formula : C28H32O6 

Molecular Weight : 464.55 

Iupac Chemical Name : FLLL32 

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SynonymsN/A 
Molecular FormulaC28H32O6 
Molecular Weight464.55 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 M.In MDA-MB-231 breast and PANC-1 pancreatic cancer cells, FLLL32 downregulates STAT3 phosphorylation and DNA-binding activity. In MDA-MB-231 cells, FLLL32 inhibit the formation of colonies and cell invasion. [1] In human multiple myeloma, glioblastoma, liver cancer, and colorectal cancer cell lines, FLLL32 also leads to the inhibition of cell proliferation and the induction of caspase-3 and PARP cleavages. 

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