Ervogastat (PF-06865571)
Catalog No: 20449
CAS Number: 2186700-33-2
Purity: ≧98.0%
Ervogastat (PF-06865571), a systemically acting diacylglycerol acyltransferase (DGAT2) inhibitor that has advanced into clinical trials for the treatment of non-alcoholic steatohepatitis (NASH) with liver fibrosis.
For research use only. We do not sell to patients.
Chemical Information
| Name | Ervogastat (PF-06865571) |
|---|---|
| Iupac Chemical Name | 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S)-oxolan-3-yl]pyrimidine-5-carboxamide |
| Synonyms | Ervogastat ; PF 06865571 ; PF-06865571 ; PF06865571 |
| Molecular Formula | C21H21N5O4 |
| Molecular Weight | 407.42 |
| Smile | O=C(C1=CN=C(C2=CC(OC3=NC=CC=C3OCC)=CN=C2)N=C1)N[C@H]4COCC4 |
| InChiKey | UKBQFBRPXKGJPY-MRXNPFEDSA-N |
| InChi | InChI=1S/C21H21N5O4/c1-2-29-18-4-3-6-23-21(18)30-17-8-14(9-22-12-17)19-24-10-15(11-25-19)20(27)26-16-5-7-28-13-16/h3-4,6,8-12,16H,2,5,7,13H2,1H3,(H,26,27)/t16-/m1/s1 |
| CAS Number | 2186700-33-2 |
| Related CAS | 2186700-33-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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