Encorafenib(LGX-818)
Catalog No: 179308
CAS Number: 1269440-17-6
Purity: >98%
Encorafenib，即LGX818LGX818 是一种可口服的突变体 B-Raf V600E 酶的抑制剂，对黑色素瘤具有良好的功效。Encorafenib 由诺华研发，目前正处于临床三期。
For research use only. We do not sell to patients.
Chemical Information
| Name | Encorafenib(LGX-818) |
|---|---|
| Iupac Chemical Name | (S)-methyl (1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate |
| Synonyms | Encorafenib;LGX818; LGX-818; LGX 818; |
| Molecular Formula | C22H27ClFN7O4S |
| Molecular Weight | 540.01 |
| Smile | O=C(OC)N[C@@H](C)CNC1=NC=CC(C2=CN(C(C)C)N=C2C3=CC(Cl)=CC(NS(=O)(C)=O)=C3F)=N1 |
| InChiKey | CMJCXYNUCSMDBY-ZDUSSCGKSA-N |
| InChi | InChI=1S/C22H27ClFN7O4S/c1-12(2)31-11-16(17-6-7-25-21(28-17)26-10-13(3)27-22(32)35-4)20(29-31)15-8-14(23)9-18(19(15)24)30-36(5,33)34/h6-9,11-13,30H,10H2,1-5H3,(H,27,32)(H,25,26,28)/t13-/m0/s1 |
| CAS Number | 1269440-17-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 类白色固体 |
|---|---|
| Purity | >98% |
| Storage | 短期可在0-4度保存，数天至数月；长期可在-20度保存三年。 |
| Solubility | 可溶于DMSO；不溶于水 |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | 产品可以在室温下运输 |
| HS Code |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
