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Elinzanetant ( NT-814 )

Catalog No.: 20259
Cas No.: 929046-33-3
Purity : ≧98.0%

Elinzanetant, previously known as NT-814 (45), is a dual NK1,3R antagonist and therefore has the potential to reduce GnRH pulsatility by blocking the endogenous effects of NKB and SP on the reproductive axis. 

For research use only. We do not sell to patients.

Chemical Information

NameElinzanetant ( NT-814 )
Iupac Chemical Name2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide
SynonymsElinzanetant ; GSK1144814A ; NT-814 ; NT 814 ; NT814 ; GSK-1144814A ; GSK 1144814A
Molecular FormulaC33H35F7N4O3
Molecular Weight668.64
SmileCC(C)(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)C(N(C2=C(C3=CC=C(F)C=C3C)C=C(N4C[C@@]5([H])COCCN5C[C@H]4CO)N=C2)C)=O
InChiKeyDWRIJNIPBUFCQS-DQEYMECFSA-N
InChiInChI=1S/C33H35F7N4O3/c1-19-9-23(34)5-6-26(19)27-13-29(44-16-25-18-47-8-7-43(25)15-24(44)17-45)41-14-28(27)42(4)30(46)31(2,3)20-10-21(32(35,36)37)12-22(11-20)33(38,39)40/h5-6,9-14,24-25,45H,7-8,15-18H2,1-4H3/t24-,25-/m0/s1
CAS Number929046-33-3
Related CAS929046-33-3

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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FormulationOff-white Solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

20259 - Elinzanetant ( NT-814 ) | CAS 929046-33-3

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