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Catalog No.: 16071025
Cas No.: 488832-69-5
Purity : 98% by HPLC 
16071025 - Elesclomol | CAS 488832-69-5

Catalog number : 16071025

CAS number : 488832-69-5

Molecular Formula : C19H20N4O2S2 

Molecular Weight : 400.52 

Iupac Chemical Name : N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide 

Smile : CN(NC(CC(=O)NN(C(=S)C1=CC=CC=C1)C)=O)C(=S)C1=CC=CC=C1


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SynonymsSTA4783; STA-4783 
Molecular FormulaC19H20N4O2S2 
Molecular Weight400.52 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
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Elesclomol, also known as STA-4783, is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway.  

488832-69-5 - Request Bulk Quote

488832-69-5 - Request Bulk Quote