Elbasvir
Catalog No: 010411
CAS Number: 1444832-51-2
Purity: 98%
Elbasvir is a HCV NS5A inhibitor, which is currently in phase 2b clinical trials as part of an all-oral, interferon-free regimen for the treatment of HCV infection. The NS5A protein plays a critical role in the replication of HCV and has been the focus of numerous research efforts over the past few years. NS5A inhibitors have shown impressive in vitro potency profiles in HCV replicon assays, making them attractive components for inclusion in all oral combination regimens.
For research use only. We do not sell to patients.
Chemical Information
| Name | Elbasvir |
|---|---|
| Iupac Chemical Name | dimethyl ((2S,2'S)-((2S,2'S)-2,2'-(5,5'-((S)-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole-3,10-diyl)bis(1H-imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl))dicarbamate |
| Synonyms | MK8742; MK-8742; MK 8742 |
| Molecular Formula | C49H55N9O7 |
| Molecular Weight | 882.02 |
| Smile | O=C(N1[C@H](C2=NC=C(C3=CC=C4C(N5[C@H](C6=CC=CC=C6)OC4=C3)=CC7=C5C=CC(C8=CN=C([C@H]9N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC9)N8)=C7)N2)CCC1)[C@@H](NC(OC)=O)C(C)C |
| InChiKey | BVAZQCUMNICBAQ-PZHYSIFUSA-N |
| InChi | InChI=1S/C49H55N9O7/c1-27(2)41(54-48(61)63-5)45(59)56-20-10-14-37(56)43-50-25-34(52-43)30-17-19-36-32(22-30)23-39-33-18-16-31(24-40(33)65-47(58(36)39)29-12-8-7-9-13-29)35-26-51-44(53-35)38-15-11-21-57(38)46(60)42(28(3)4)55-49(62)64-6/h7-9,12-13,16-19,22-28,37-38,41-42,47H,10-11,14-15,20-21H2,1-6H3,(H,50,52)(H,51,53)(H,54,61)(H,55,62)/t37-,38-,41-,42-,47-/m0/s1 |
| CAS Number | 1444832-51-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
