EX-527 R-enantiomer
Catalog No: 17011801
CAS Number: 848193-69-1
Purity: 98%
EX-527 R-enantiomer is a negative control of the active form EX-527 S-enantiomer(Speculated for reference); IC50 > 100 uM, e1/e2 can be found in the reference paper.
EX-527 S-enantiomer is the S-enantiomer of EX-527, EX-527 racemic has an IC50 of 98 nM for SIRT1, in the reference paper,
Compound 35S has good potency than 35R, so we speculate that EX-527 S enantiomer is the active form vs R enantiomer. Just for reference!
For research use only. We do not sell to patients.
Chemical Information
| Name | EX-527 R-enantiomer |
|---|---|
| Iupac Chemical Name | (R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Synonyms | Selisistat R-enantiomer; |
| Molecular Formula | C₁₃H₁₃ClN₂O |
| Molecular Weight | 248.71 |
| Smile | O=C([C@H]1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N |
| InChiKey | FUZYTVDVLBBXDL-SECBINFHSA-N |
| InChi | InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1 |
| CAS Number | 848193-69-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
