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EX-527 R-enantiomer

Catalog No.: 17011801
Cas No.: 848193-69-1
Purity : 98% 

EX-527 R-enantiomer is a negative control of the active form EX-527 S-enantiomer(Speculated for reference); IC50 > 100 uM, e1/e2 can be found in the reference paper.

EX-527 S-enantiomer is the S-enantiomer of EX-527, EX-527 racemic has an IC50 of 98 nM for SIRT1, in the reference paper,

Compound 35S has good potency than 35R, so we speculate that EX-527 S enantiomer is the active form vs R enantiomer. Just for reference! 

For research use only. We do not sell to patients.

Chemical Information

NameEX-527 R-enantiomer
Iupac Chemical Name (R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
SynonymsSelisistat R-enantiomer; 
Molecular FormulaC₁₃H₁₃ClN₂O 
Molecular Weight248.71 
SmileO=C([C@H]1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N
InChiKeyFUZYTVDVLBBXDL-SECBINFHSA-N
InChiInChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1
CAS Number848193-69-1
Related CAS

Ordering Information

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FormulationOff-white solid to white solid
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17011801 - EX-527 R-enantiomer | CAS 848193-69-1

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