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ENMD-2076

Catalog No: 111909
CAS Number: 934353-76-1
Purity: 98% 

ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFR. 

For research use only. We do not sell to patients.

Chemical Information

NameENMD-2076
Iupac Chemical Name6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine 
SynonymsENMD 2076; ENMD2076; cc-471 
Molecular FormulaC21H25N7 
Molecular Weight375.47 
SmileCC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)C=CC4=CC=CC=C4
InChiKeyBLQYVHBZHAISJM-UHFFFAOYSA-N
InChiInChI=1S/C21H25N7/c1-16-14-20(26-25-16)23-19-15-21(28-12-10-27(2)11-13-28)24-18(22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3,(H2,22,23,24,25,26)
CAS Number934353-76-1
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

111909 - ENMD-2076 | CAS 934353-76-1

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