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E7449

Catalog No.: 178903
Cas No.: 1140964-99-3
Purity : 98.0% 
178903 - E7449 | CAS 1140964-99-3

Catalog number : 178903

CAS number : 1140964-99-3

Molecular Formula : C18H15N5O 

Molecular Weight : 317.34 

Iupac Chemical Name : 8-(isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one 

Smile : C1N(CC2=CC=CC=C12)CC1=NC=2C=CC=C3C2C(N1)=NNC3=O

InChiKey : JLFSBHQQXIAQEC-UHFFFAOYSA-N

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SynonymsE7449;E 7449;E-7449 
Molecular FormulaC18H15N5O 
Molecular Weight317.34 
Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1N(CC2=CC=CC=C12)CC1=NC=2C=CC=C3C2C(N1)=NNC3=O
InChiKeyJLFSBHQQXIAQEC-UHFFFAOYSA-N
InChiInChI=1S/C18H15N5O/c24-18-13-6-3-7-14-16(13)17(21-22-18)20-15(19-14)10-23-8-11-4-1-2-5-12(11)9-23/h1-7H,8-10H2,(H,22,24)(H,19,20,21)
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E7449 is an orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. 

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