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E7449

Catalog No: 178903
CAS Number: 1140964-99-3
Purity: 98.0% 

E7449 is an orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. 

For research use only. We do not sell to patients.

Chemical Information

NameE7449
Iupac Chemical Name8-(isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one 
SynonymsE7449;E 7449;E-7449 
Molecular FormulaC18H15N5O 
Molecular Weight317.34 
SmileC1N(CC2=CC=CC=C12)CC1=NC=2C=CC=C3C2C(N1)=NNC3=O
InChiKeyJLFSBHQQXIAQEC-UHFFFAOYSA-N
InChiInChI=1S/C18H15N5O/c24-18-13-6-3-7-14-16(13)17(21-22-18)20-15(19-14)10-23-8-11-4-1-2-5-12(11)9-23/h1-7H,8-10H2,(H,22,24)(H,19,20,21)
CAS Number1140964-99-3
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

178903 - E7449 | CAS 1140964-99-3

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