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Dinaciclib(SCH-727965)

Catalog No: 63010
CAS Number: 779353-01-4
Purity: >98% by HPLC 

Dinaciclib is a novel potent small molecule inhibitor of cyclin-dependent kinases (CDK)1, CDK2, CDK5, and CDK9. Patients with relapsed multiple myeloma and 5 prior lines of therapy, with measurable disease, were enrolled.

 

For research use only. We do not sell to patients.

Chemical Information

NameDinaciclib(SCH-727965)
Iupac Chemical Name(S)-3-(((3-Ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide 
SynonymsSCH727965 
Molecular FormulaC21H28N6O2 
Molecular Weight396.49 
SmileC(C)C=1C=NN2C1N=C(C=C2NCC=2C=[N+](C=CC2)[O-])N2[C@@H](CCCC2)CCO
InChiKeyPIMQWRZWLQKKBJ-SFHVURJKSA-N
InChiInChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1
CAS Number779353-01-4
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity>98% by HPLC 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

63010 - Dinaciclib(SCH-727965) | CAS 779353-01-4

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