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Dinaciclib(SCH-727965)

Catalog No.: 63010
Cas No.: 779353-01-4
Purity : >98% by HPLC 
63010 - Dinaciclib(SCH-727965) | CAS 779353-01-4

Catalog number : 63010

CAS number : 779353-01-4

Molecular Formula : C21H28N6O2 

Molecular Weight : 396.49 

Iupac Chemical Name : (S)-3-(((3-Ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide 

Smile : C(C)C=1C=NN2C1N=C(C=C2NCC=2C=[N+](C=CC2)[O-])N2[C@@H](CCCC2)CCO

InChiKey : PIMQWRZWLQKKBJ-SFHVURJKSA-N

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SynonymsSCH727965 
Molecular FormulaC21H28N6O2 
Molecular Weight396.49 
Appearancecrystalline solid 
Purity>98% by HPLC 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileC(C)C=1C=NN2C1N=C(C=C2NCC=2C=[N+](C=CC2)[O-])N2[C@@H](CCCC2)CCO
InChiKeyPIMQWRZWLQKKBJ-SFHVURJKSA-N
InChiInChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1
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Dinaciclib is a novel potent small molecule inhibitor of cyclin-dependent kinases (CDK)1, CDK2, CDK5, and CDK9. Patients with relapsed multiple myeloma and 5 prior lines of therapy, with measurable disease, were enrolled.

 

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