DSR-6434
Catalog No: 20497
CAS Number: 1059070-10-8
Purity: 98% Min.
DSR-6434 is a potent TLR7 agonist (EC50 = 7.2 nM). DSR-6434 activates several immune effector cells in vitro. DSR-6434 indicated an optimal balance between the agonistic potency and high water solubility. It also demonstrated a strong antitumor effect in vivo by intravenous administration in a tumor bearing mice model.
For research use only. We do not sell to patients.
Chemical Information
| Name | DSR-6434 |
|---|---|
| Iupac Chemical Name | 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one |
| Synonyms | DSR-6434; DSR 6434; DSR6434; |
| Molecular Formula | C19H28N8O2 |
| Molecular Weight | 400.48 |
| Smile | O=C1NC2=C(N)N=C(NCCCC)N=C2N1CC3=CC=C(OCCN(C)C)N=C3 |
| InChiKey | SSZHESNDOMBSRV-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H28N8O2/c1-4-5-8-21-18-24-16(20)15-17(25-18)27(19(28)23-15)12-13-6-7-14(22-11-13)29-10-9-26(2)3/h6-7,11H,4-5,8-10,12H2,1-3H3,(H,23,28)(H3,20,21,24,25) |
| CAS Number | 1059070-10-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
