D4476
编号: 102611
Cas号: 301836-43-1
纯度: 98%
D4476, a cell-permeant inhibitor of CK1_delta_ (IC90 <10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5.
For research use only. We do not sell to patients.
化学信息
| 名称 | D4476 |
|---|---|
| Iupac 化学名称 | 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide |
| 同义词 | Casein Kinase I Inhibitor; D 4476; D-4476 |
| 分子式 | C23H18N4O3 |
| 分子量 | 398.41 |
| Smile | C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
| InChiKey | DPDZHVCKYBCJHW-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27) |
| Cas号 | 301836-43-1 |
| Related CAS |
订购信息
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