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D4476

Catalog No.: 102611
Cas No.: 301836-43-1
Purity : 98% 
102611 - D4476 | CAS 301836-43-1

Catalog number : 102611

CAS number : 301836-43-1

Molecular Formula : C23H18N4O3 

Molecular Weight : 398.41 

Iupac Chemical Name : 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide 

Smile : C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

InChiKey : DPDZHVCKYBCJHW-UHFFFAOYSA-N

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SynonymsCasein Kinase I Inhibitor; D 4476; D-4476 
Molecular FormulaC23H18N4O3 
Molecular Weight398.41 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChiKeyDPDZHVCKYBCJHW-UHFFFAOYSA-N
InChiInChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
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D4476, a cell-permeant inhibitor of CK1_delta_ (IC90 <10 uM), suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a, D4476 originally identified as inhibitors of activin receptor-like kinase ALK5. 

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