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Cobimetinib

Catalog No: 102203
CAS Number: 934660-93-2
Purity: 98% 

Cobimetinib is an orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity. 

For research use only. We do not sell to patients.

Chemical Information

NameCobimetinib
Iupac Chemical Name[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone 
SynonymsXL518; GDC 0973; EUI 
Molecular FormulaC21H21F3IN3O2 
Molecular Weight531.31 
SmileFC=1C(=C(C=CC1F)C(=O)N1CC(C1)([C@H]1NCCCC1)O)NC1=C(C=C(C=C1)I)F
InChiKeyBSMCAPRUBJMWDF-KRWDZBQOSA-N
InChiInChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1
CAS Number934660-93-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

102203 - Cobimetinib | CAS 934660-93-2

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