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Centanafadine HCl

Catalog No.: 21236
Cas No.: 923981-14-0
Purity : ≧98.0%

Centanafadine, also known as EB-1020, is an adrenergic uptake inhibitor and dopamine uptake inhibitor and serotonin uptake inhibitor. Centanafadine modulates norepinephrine, dopamine and, to a lesser extent, serotonin reuptake in a ratio of 1:6:14, respectively to improve focus, attention and executive function.

For research use only. We do not sell to patients.

Chemical Information

NameCentanafadine HCl
Iupac Chemical Name(1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochoride
SynonymsEB-1020 ; EB 1020 ; EB1020 ; EB-1020 SR ; CTN SR ; Centanafadine
Molecular FormulaC15H16ClN
Molecular Weight245.75
Smile[H][C@@]12CNC[C@]1(C3=CC=C4C=CC=CC4=C3)C2.[H]Cl
InChiKey ACVMJAJGCQUPKX-LIOBNPLQSA-N
InChi InChI=1S/C15H15N.ClH/c1-2-4-12-7-13(6-5-11(12)3-1)15-8-14(15)9-16-10-15;/h1-7,14,16H,8-10H2;1H/t14-,15+;/m1./s1
CAS Number923981-14-0
Related CAS924012-43-1 (free base) 923981-14-0 (HCl)

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2933999701
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Targets
Mechanism
Cell study
Animal study
Clinical study

1: Bymaster FP, Golembiowska K, Kowalska M, Choi YK, Tarazi FI. Pharmacological
characterization of the norepinephrine and dopamine reuptake inhibitor EB-1020:
implications for treatment of attention-deficit hyperactivity disorder. Synapse.
2012 Jun;66(6):522-32. doi: 10.1002/syn.21538. Epub 2012 Feb 22. PubMed PMID:
22298359.

Chemical Structure

21236 - Centanafadine HCl | CAS 923981-14-0

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