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Cambinol

Catalog No.: 178313
Cas No.: 14513-15-6
Purity : 98.0%
178313 - Cambinol | CAS 14513-15-6

Catalog number : 178313

CAS number : 14513-15-6

Molecular Formula : C21H16N2O2S

Molecular Weight : 360.43

Iupac Chemical Name : 5-((2-hydroxynaphthalen-1-yl)methyl)-6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Smile : OC1=C(C2=CC=CC=C2C=C1)CC=1C(NC(NC1C1=CC=CC=C1)=S)=O

InChiKey : RVNSQVIUFZVNAU-UHFFFAOYSA-N

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SynonymsSIRT 1/2 inhibitor IV; NSC112546; NSC-112546; NSC 112546; SIRT1 Inhibitor II; SIRT2 Inhibitor VI.
Molecular FormulaC21H16N2O2S
Molecular Weight360.43
Appearanceoff-white solid
Purity98.0%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
SmileOC1=C(C2=CC=CC=C2C=C1)CC=1C(NC(NC1C1=CC=CC=C1)=S)=O
InChiKeyRVNSQVIUFZVNAU-UHFFFAOYSA-N
InChiInChI=1S/C21H16N2O2S/c24-18-11-10-13-6-4-5-9-15(13)16(18)12-17-19(14-7-2-1-3-8-14)22-21(26)23-20(17)25/h1-11,24H,12H2,(H2,22,23,25,26)
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Cambinol is a SIRT inhibitor. It inhibits expression of pro-inflammatory cytokines, improves survival in models of endotoxic shock and septic shock.

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