CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. 
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Chemical Information 
Name CaMKII-IN-1  
Synonyms N-[6-benzyl-2-(2-phenylethylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]-3-chloro-2-methylbenzenesulfonamide   
Molecular Formula C29H30ClN5O2S   
Molecular Weight 548.1   
Smile CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=NC(=NC3=C2CN(CC3)CC4=CC=CC=C4)NCCC5=CC=CC=C5  
InChiKey LGUUETDTMQTHML-UHFFFAOYSA-N  
InChi InChI=1S/C29H30ClN5O2S/c1-21-25(30)13-8-14-27(21)38(36,37)34-28-24-20-35(19-23-11-6-3-7-12-23)18-16-26(24)32-29(33-28)31-17-15-22-9-4-2-5-10-22/h2-14H,15-20H2,1H3,(H2,31,32,33,34)  
CAS Number 1208123-85-6  
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Ordering Information 
Packaging Price Availability Purity Shipping Time  
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Formulation Solid powder   
Purity 98%   
Storage -20 ºC for 3 years   
Solubility Soluble in DMSO   
Handling  
Shipping Condition Shipped under ambient temperature   
HS Code  
 
Targets  
Mechanism  
Cell study  
Animal study  
Clinical study