CX-4945(Silmitasertib)
Catalog No: 52024
CAS Number: 1009820-21-6
Purity: 98%
Silmitasertib (CX-4945) is a potent and selective orally bioavailable small molecule inhibitor of Casein kinase II (CK2). The antiproliferative activity of CX-4945 against cancer cells correlated with expression levels of the CK2α catalytic subunit. CX-4945 caused cell-cycle arrest and selectively induced apoptosis in cancer cells relative to normal cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | CX-4945(Silmitasertib) |
|---|---|
| Iupac Chemical Name | 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid |
| Synonyms | CX-4945;Silmitasertib;CX4945;CX 4945 |
| Molecular Formula | C19H12ClN3O2 |
| Molecular Weight | 349.77 |
| Smile | ClC=1C=C(C=CC1)NC1=NC2=C(C3=CN=CC=C13)C=CC(=C2)C(=O)O |
| InChiKey | MUOKSQABCJCOPU-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) |
| CAS Number | 1009820-21-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | yellow solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
