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CRT0273750

Catalog No.: 20258
Cas No.: 1979939-16-6
Purity : ≧98.0%

CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.

For research use only. We do not sell to patients.

Chemical Information

NameCRT0273750
Iupac Chemical Name(S)-N-(1-(4-chlorophenyl)ethyl)-3-(3-(4-(trifluoromethoxy)benzyl)-3H-imidazo[4,5-b]pyridin-2-yl)propanamide
SynonymsCRT0273750 ; CRT 0273750 ; CRT-0273750
Molecular FormulaC25H22ClF3N4O2
Molecular Weight502.92
SmileFC(F)(F)OC1=CC=C(CN2C(CCC(N[C@@H](C)C3=CC=C(C=C3)Cl)=O)=NC4=CC=CN=C42)C=C1
InChiKeyHXYXHSDYBDFOFO-INIZCTEOSA-N
InChiInChI=1S/C25H22ClF3N4O2/c1-16(18-6-8-19(26)9-7-18)31-23(34)13-12-22-32-21-3-2-14-30-24(21)33(22)15-17-4-10-20(11-5-17)35-25(27,28)29/h2-11,14,16H,12-13,15H2,1H3,(H,31,34)/t16-/m0/s1
CAS Number1979939-16-6
Related CAS1979939-16-6

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

1: Shah P, Cheasty A, Foxton C, Raynham T, Farooq M, Gutierrez IF, Lejeune A, Pritchard M, Turnbull A, Pang L, Owen P, Boyd S, Stowell A, Jordan A, Hamilton NM, Hitchin JR, Stockley M, MacDonald E, Quesada MJ, Trivier E, Skeete J, Ovaa H, Moolenaar WH, Ryder H.
Discovery of potent inhibitors of the lysophospholipase autotaxin. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5403-5410. doi: 10.1016/j.bmcl.2016.10.036. Epub 2016 Oct 14. PubMed PMID: 27780639.

Chemical Structure

20258 - CRT0273750 | CAS 1979939-16-6

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