CRANAD-28
Catalog No: 20478
CAS Number: 1623747-97-6
Purity: 98% Min.
CRANAD-28 is a blood brain barrier (BBB) penetrable two-photon imaging probe. It acts by labelling plaques and cerebral amyloid angiopathies (CAAs).
For research use only. We do not sell to patients.
Chemical Information
| Name | CRANAD-28 |
|---|---|
| Iupac Chemical Name | (E)-4-(2-(2,2-difluoro-6-(2-(5-methyl-1-phenyl-1H-pyrazol-4-yl)ethyl)-2H-1,3l3,2l4-dioxaborinin-4-yl)vinyl)-5-methyl-1-phenyl-1H-pyrazole |
| Synonyms | CRANAD-28; CRANAD 28; CRANAD28; |
| Molecular Formula | C27H25BF2N4O2 |
| Molecular Weight | 486.32 |
| Smile | CC1=C(/C=C/C2=OB(F)(F)OC(CCC3=C(C)N(C4=CC=CC=C4)N=C3)=C2)C=NN1C5=CC=CC=C5 |
| InChiKey | WXJHBEAKOQMUQO-FYWRMAATSA-N |
| InChi | InChI=1S/C27H25BF2N4O2/c1-20-22(18-31-33(20)24-9-5-3-6-10-24)13-15-26-17-27(36-28(29,30)35-26)16-14-23-19-32-34(21(23)2)25-11-7-4-8-12-25/h3-13,15,17-19H,14,16H2,1-2H3/b15-13+ |
| CAS Number | 1623747-97-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C. A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease. Chem Commun (Camb). 2014 Oct 9;50(78):11550-3. doi: 10.1039/c4cc03731f. PubMed PMID: 25134928; PubMed Central PMCID: PMC4617557.
Chemical Structure
