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Lirametostat ( CPI-1205 )

Catalog No.: 16122736
Cas No.: 1621862-70-1
Purity : ≧98.0%

CPI-1205 is a potent, selective, and cofactor-competitive inhibitor of wild type and mutant EZH2 catalytic activity, which demonstrates anti-proliferative effects in prostate and other cancer cell models. 

For research use only. We do not sell to patients.

Chemical Information

NameLirametostat ( CPI-1205 )
Iupac Chemical Name(R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide
Synonyms CPI-1205 ; CPI 1205 ; CPI1205 ; Lirametostat
Molecular FormulaC27H33F3N4O3 
Molecular Weight518.57 
SmileO=C(C1=C(C)N([C@@H](C2CCN(CC(F)(F)F)CC2)C)C3=C1C=CC=C3)NCC4=C(OC)C=C(C)NC4=O
InChiKeyHPODOLXTMDHLLC-QGZVFWFLSA-N
InChiInChI=1S/C27H33F3N4O3/c1-16-13-23(37-4)21(25(35)32-16)14-31-26(36)24-18(3)34(22-8-6-5-7-20(22)24)17(2)19-9-11-33(12-10-19)15-27(28,29)30/h5-8,13,17,19H,9-12,14-15H2,1-4H3,(H,31,36)(H,32,35)/t17-/m1/s1
CAS Number1621862-70-1
Related CAS1621862-70-1

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO 
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122736 - Lirametostat ( CPI-1205 ) | CAS 1621862-70-1

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