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CP-673451

Catalog No.: 16070704
Cas No.: 343787-29-1
Purity : 98% by HPLC 
16070704 - CP-673451 | CAS 343787-29-1

Catalog number : 16070704

CAS number : 343787-29-1

Molecular Formula : C24H27N5O2 

Molecular Weight : 417.5 

Iupac Chemical Name : 1-(2-(5-(2-Methoxyethoxy)benzimidazol-1-yl)quinolin-8-yl)piperidin-4-ylamine 

Smile : COCCOC1=CC2=C(N(C=N2)C2=NC3=C(C=CC=C3C=C2)N2CCC(CC2)N)C=C1

InChiKey : DEEOXSOLTLIWMG-UHFFFAOYSA-N

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SynonymsCP-673,451; CP-673451; 
Molecular FormulaC24H27N5O2 
Molecular Weight417.5 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCOCCOC1=CC2=C(N(C=N2)C2=NC3=C(C=CC=C3C=C2)N2CCC(CC2)N)C=C1
InChiKeyDEEOXSOLTLIWMG-UHFFFAOYSA-N
InChiInChI=1S/C24H27N5O2/c1-30-13-14-31-19-6-7-21-20(15-19)26-16-29(21)23-8-5-17-3-2-4-22(24(17)27-23)28-11-9-18(25)10-12-28/h2-8,15-16,18H,9-14,25H2,1H3
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CP-673451 is a selective inhibitor of PDGFR/ with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, and has anti-angiogenic and anti-tumor activity. 

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