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CLP-290 Catalog No : 193286

Chemical Information

Product NameCLP-290
Iupac Chemical Name[5-Fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl] pyrrolidine-1-carboxylate
SynonymsCLP290; CLP 290; CLP-290
Molecular FormulaC19H21FN4O3S
Molecular Weight404.4604
SmileO=C(N1CCCC1)OC2=CC(F)=CC=C2/C=C(SC(N3CCCCN3)=N4)/C4=O
InChiKeyDIXMMXNNKLCLOM-WJDWOHSUSA-N
InChiInChI=1S/C19H21FN4O3S/c20-14-6-5-13(15(12-14)27-19(26)23-8-3-4-9-23)11-16-17(25)22-18(28-16)24-10-2-1-7-21-24/h5-6,11-12,21H,1-4,7-10H2/b16-11-
Cas1181083-81-7

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

CLP-290 is a novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transporters.

Chemical Structure

193286 - CLP-290  | CAS 1181083-81-7

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