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Catalog No.: 16053104
Cas No.: 163042-96-4
Purity : 98% by HPLC 
16053104 - CF-102 | CAS 163042-96-4

Catalog number : 16053104

CAS number : 163042-96-4

Molecular Formula : C18H18ClIN6O4 

Molecular Weight : 544.73079 

Iupac Chemical Name : (2S,3S,4R,5R)-5-(2-chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide 

Smile : ClC1=NC(=C2N=CN(C2=N1)[C@H]1[C@@H]([C@@H]([C@H](O1)C(=O)NC)O)O)NCC1=CC(=CC=C1)I


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SynonymsCF 102; Cl-IB-MECA; 2-Cl-IB-MECA 
Molecular FormulaC18H18ClIN6O4 
Molecular Weight544.73079 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
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CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly selective adenosine A3 receptor (A3AR) agonist with potential antineoplastic activity. Adenosine A3 receptor agonist CF102 selectively binds to and activates the cell surface-expressed A3AR, deregulating Wnt and NF-kB signal transduction pathways downstream, which may result in apoptosis of A3AR-expressing tumor cells. A3AR, a G protein-coupled receptor, is highly expressed on the cell surfaces of various solid tumor cell types, including hepatocellular carcinoma (HCC) cells, and plays an important role in cellular proliferation 

163042-96-4 - Request Bulk Quote

163042-96-4 - Request Bulk Quote