+86-27-65522453 sales@sun-shinechem.com

CF-102

Catalog No.: 16053104
Cas No.: 163042-96-4
Purity : 98% by HPLC 
16053104 - CF-102 | CAS 163042-96-4

Catalog number : 16053104

CAS number : 163042-96-4

Molecular Formula : C18H18ClIN6O4 

Molecular Weight : 544.73079 

Iupac Chemical Name : (2S,3S,4R,5R)-5-(2-chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide 

Smile : ClC1=NC(=C2N=CN(C2=N1)[C@H]1[C@@H]([C@@H]([C@H](O1)C(=O)NC)O)O)NCC1=CC(=CC=C1)I

InChiKey : IPSYPUKKXMNCNQ-PFHKOEEOSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsCF 102; Cl-IB-MECA; 2-Cl-IB-MECA 
Molecular FormulaC18H18ClIN6O4 
Molecular Weight544.73079 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileClC1=NC(=C2N=CN(C2=N1)[C@H]1[C@@H]([C@@H]([C@H](O1)C(=O)NC)O)O)NCC1=CC(=CC=C1)I
InChiKeyIPSYPUKKXMNCNQ-PFHKOEEOSA-N
InChiInChI=1S/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1
Coming soon.
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly selective adenosine A3 receptor (A3AR) agonist with potential antineoplastic activity. Adenosine A3 receptor agonist CF102 selectively binds to and activates the cell surface-expressed A3AR, deregulating Wnt and NF-kB signal transduction pathways downstream, which may result in apoptosis of A3AR-expressing tumor cells. A3AR, a G protein-coupled receptor, is highly expressed on the cell surfaces of various solid tumor cell types, including hepatocellular carcinoma (HCC) cells, and plays an important role in cellular proliferation 

163042-96-4 - Request Bulk Quote

×
163042-96-4 - Request Bulk Quote
Change