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CC-122

Catalog No.: 17030313
Cas No.: 1015474-32-4
Purity : 98% 
17030313 - CC-122 | CAS 1015474-32-4

Catalog number : 17030313

CAS number : 1015474-32-4

Molecular Formula : C14H14N4O3 

Molecular Weight : 286.291 

Iupac Chemical Name : 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione 

Smile : NC1=C2C(N(C(=NC2=CC=C1)C)C1C(NC(CC1)=O)=O)=O

InChiKey : RSNPAKAFCAAMBH-UHFFFAOYSA-N

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SynonymsCC 122; CC-122; CC122;Avadomide 
Molecular FormulaC14H14N4O3 
Molecular Weight286.291 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileNC1=C2C(N(C(=NC2=CC=C1)C)C1C(NC(CC1)=O)=O)=O
InChiKeyRSNPAKAFCAAMBH-UHFFFAOYSA-N
InChiInChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)
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CC-122 is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects. 

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