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CC-115 hydrochloride

Catalog No.: 611815
Cas No.: 1300118-55-1
Purity : 98% 
611815 - CC-115 hydrochloride | CAS 1300118-55-1

Catalog number : 611815

CAS number : 1300118-55-1

Molecular Formula : C16H17ClN8O 

Molecular Weight : 372.81 

Iupac Chemical Name : CC-115 (hydrochloride) 

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Molecular FormulaC16H17ClN8O 
Molecular Weight372.81 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).


CC-115 shows good PK profiles across multiple species with 53%, 76%, and 100% oral bioavailability in mouse, rat, and dog, respectively. CC-115, with favorable physicochemical and pharmacokinetic properties, demonstrates mTOR pathway inhibition and tumor growth inhibition, as well as a good safety profile, suitable for clinical development.


 

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