Brepocitinib ( PF-06700841 )
Catalog No: 232251
CAS Number: 1883299-62-4
Purity: ≧98.0%
Brepocitinib 是一种潜在的 TYK2 和 JAK1双重选择性抑制剂，IC50 分别为 17 nM 和 23 nM。
For research use only. We do not sell to patients.
Chemical Information
| Name | Brepocitinib ( PF-06700841 ) |
|---|---|
| Iupac Chemical Name | ((S)-2,2-difluorocyclopropyl)((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone |
| Synonyms | PF-06700841 ; PF 06700841 ; PF06700841 ; Brepocitinib |
| Molecular Formula | C18H21F2N7O |
| Molecular Weight | 389.40 |
| Smile | O=C([C@H]1C(F)(F)C1)N2[C@@]3([H])CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)C[C@]2([H])CC3 |
| InChiKey | BUWBRTXGQRBBHG-MJBXVCDLSA-N |
| InChi | InChI=1S/C18H21F2N7O/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24)/t12-,13+,14-/m0/s1 |
| CAS Number | 1883299-62-4 |
| Related CAS | 2140301-96-6 (tosylate) 1883299-62-4 (free base) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | 固体粉末 |
|---|---|
| Purity | ≧98.0% |
| Storage | 0-4℃，可保存几天到几周；-20℃，可保存 几个月。 |
| Solubility | 溶于DMSO等有机溶剂 |
| Handling | Refer to MSDS |
| Shipping Condition | 可以在室温下进行运输。 |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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