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Baricitinib

Catalog No.: 51908
Cas No.: 1187594-09-7
Purity : 98% 
51908 - Baricitinib | CAS 1187594-09-7

Catalog number : 51908

CAS number : 1187594-09-7

Molecular Formula : C16H17N7O2S 

Molecular Weight : 371.42 

Iupac Chemical Name : 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]- 

Smile : C(C)S(=O)(=O)N1CC(C1)(CC#N)N1N=CC(=C1)C=1C2=C(N=CN1)NC=C2

InChiKey : XUZMWHLSFXCVMG-UHFFFAOYSA-N

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SynonymsBaricitinib;LY3009104;INCB028050 
Molecular FormulaC16H17N7O2S 
Molecular Weight371.42 
Appearancewhite solid 
Purity98% 
Solubility5mg/ml in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature. 
SmileC(C)S(=O)(=O)N1CC(C1)(CC#N)N1N=CC(=C1)C=1C2=C(N=CN1)NC=C2
InChiKeyXUZMWHLSFXCVMG-UHFFFAOYSA-N
InChiInChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
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Baricitinib (also known as LY3009104 or INCB028050) is a novel and potent small molecule inhibitor of Janus kinase family of enzymes (JAKs) with selectivity for JAK1 and JAK2. Baricitinib is currently in clinical development for the treatment of rheumatoid arthritis (RA) and other inflammatory disorders.
Baricitinib is already in Phase III for RA and in Phase II for psoriasis and diabetic nephropathy.

 

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