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BMS-777607

Catalog No.: 121417
Cas No.: 1025720-94-8
Purity : 98% 

BMS-777607 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. MET tyrosine kinase inhibitor BMS-777607 binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway. 

For research use only. We do not sell to patients.

Chemical Information

NameBMS-777607
Iupac Chemical NameN-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamide 
SynonymsBMS777607 ; BMS 777607  ; BMS-777607
Molecular FormulaC25H19ClF2N4O4 
Molecular Weight512.893 
SmileCCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
InChiKeyVNBRGSXVFBYQNN-UHFFFAOYSA-N
InChiInChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
CAS Number1025720-94-8
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Ordering Information

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FormulationOff-white Solid powder to light-yellow solid 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code2933290090
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

121417 - BMS-777607 | CAS 1025720-94-8

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