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Catalog No.: 16062903
Cas No.: 623152-17-0
Purity : 98% by HPLC 
16062903 - BMS-582949 | CAS 623152-17-0

Catalog number : 16062903

CAS number : 623152-17-0

Molecular Formula : C22H26N6O2 

Molecular Weight : 406.49 

Iupac Chemical Name : 4-((5-(cyclopropylcarbamoyl)-2-methylphenyl)amino)-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 

Smile : C1(CC1)NC(=O)C=1C=CC(=C(C1)NC1=NC=NN2C1=C(C(=C2)C(=O)NCCC)C)C


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SynonymsBMS-582949; BMS 582949; 
Molecular FormulaC22H26N6O2 
Molecular Weight406.49 
AppearanceSolid powder 
Purity98% by HPLC 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
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BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor. BMS-582949 is currently under Phase II clinical trials for the treatment of inflammatory diseases. One clinical study showed that, in stable atherosclerosis, 12 weeks of treatment with BMS-582949 did not reduce arterial inflammation or hs-CRP compared to placebo, whereas intensification of statin therapy significantly decreased arterial inflammation. p38 MAP kinase plays a crucial role in regulating the biosynthesis of many inflammatory cytokines including TNF and IL-1 

623152-17-0 - Request Bulk Quote

623152-17-0 - Request Bulk Quote