BLU-285
Catalog No: 1781003
CAS Number: 1703793-34-3
Purity: 98.0%
BLU-285 is a potent and selective inhibitor of PDGFR D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease.
For research use only. We do not sell to patients.
Chemical Information
| Name | BLU-285 |
|---|---|
| Iupac Chemical Name | (S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine |
| Synonyms | BLU-285|BLU 285|BLU285|Avapritinib |
| Molecular Formula | C26H27FN10 |
| Molecular Weight | 498.5704 |
| Smile | FC1=CC=C(C=C1)[C@](C)(N)C=1C=NC(=NC1)N1CCN(CC1)C1=NC=NN2C1=CC(=C2)C=2C=NN(C2)C |
| InChiKey | DWYRIWUZIJHQKQ-SANMLTNESA-N |
| InChi | InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1 |
| CAS Number | 1703793-34-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
