BIIB021
Catalog No: 16122868
CAS Number: 848695-25-0
Purity: 98%
BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations.
For research use only. We do not sell to patients.
Chemical Information
| Name | BIIB021 |
|---|---|
| Iupac Chemical Name | BIIB021 |
| Synonyms | BIIB 021; BIIB-021; CNF-2024; CNF 2024; CNF2024 |
| Molecular Formula | C14H15ClN6O |
| Molecular Weight | 318.76 |
| Smile | Cc1cnc(c(c1OC)C)Cn2cnc3c2nc(nc3Cl)N |
| InChiKey | QULDDKSCVCJTPV-UHFFFAOYSA-N |
| InChi | InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20) |
| CAS Number | 848695-25-0 |
| MDL | MFCD15528939 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
