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BI-187004

Catalog No: 21224
CAS Number: 1303515-32-3
Purity: ≧98.0%

BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.

For research use only. We do not sell to patients.

Chemical Information

Name BI-187004
Iupac Chemical Name(4aR,9aS)-1-(1H-Benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile
SynonymsBI-187004 ; BI 187004 ; BI187004 ; VTP-34072 ; VTP 34072 ; VTP34072
Molecular FormulaC21H18N4O
Molecular Weight342.402
SmileO=C(N(CCC1)[C@]2(CC3=C(C=C(C=C3)C#N)[C@@]12[H])[H])C4=CC=C5N=CNC5=C4
InChiKeyVVZNCSHIBODHMZ-UZLBHIALSA-N
InChi InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1
CAS Number1303515-32-3
Related CAS1303515-32-3

Ordering Information

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Formulation类白色至白色固体
Purity≧98.0%
Storage短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
Solubility可溶于DMSO
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping Condition可在常温下运输
HS Code2933999701
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

Maw HH, Zeng X, Campbell S, Taub ME, Teitelbaum AM. N-Methylation of BI 187004 by Thiol S-Methyltransferase. Drug Metab Dispos. 2018 Jun;46(6):770-778. doi: 10.1124/dmd.117.079764. Epub 2018 Mar 7. PMID: 29514826.

Chemical Structure

21224 -  BI-187004 | CAS 1303515-32-3

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