BI-187004
Catalog No: 21224
CAS Number: 1303515-32-3
Purity: ≧98.0%
BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | BI-187004 |
|---|---|
| Iupac Chemical Name | (4aR,9aS)-1-(1H-Benzimidazol-6-ylcarbonyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile |
| Synonyms | BI-187004 ; BI 187004 ; BI187004 ; VTP-34072 ; VTP 34072 ; VTP34072 |
| Molecular Formula | C21H18N4O |
| Molecular Weight | 342.402 |
| Smile | O=C(N(CCC1)[C@]2(CC3=C(C=C(C=C3)C#N)[C@@]12[H])[H])C4=CC=C5N=CNC5=C4 |
| InChiKey | VVZNCSHIBODHMZ-UZLBHIALSA-N |
| InChi | InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1 |
| CAS Number | 1303515-32-3 |
| Related CAS | 1303515-32-3 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | 2933999701 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Maw HH, Zeng X, Campbell S, Taub ME, Teitelbaum AM. N-Methylation of BI 187004 by Thiol S-Methyltransferase. Drug Metab Dispos. 2018 Jun;46(6):770-778. doi: 10.1124/dmd.117.079764. Epub 2018 Mar 7. PMID: 29514826.
Chemical Structure
