BI 44370
Catalog No: 26A043
CAS Number: 866086-05-7
Purity: ≧98.0%
BI 44370 was developed as a calcitonin gene-related peptide (CGRP) receptor antagonist for the treatment of acute migraine attacks.
For research use only. We do not sell to patients.
Chemical Information
| Name | BI 44370 |
|---|---|
| Iupac Chemical Name | (R)-3-(4-hydroxy-3,5-dimethylphenyl)-1-(4-morpholinopiperidin-1-yl)-1-oxopropan-2-yl 4-(2-oxo-1,2,4,5-tetrahydro-3H-benzo[d][1,3]diazepin-3-yl)piperidine-1-carboxylate |
| Synonyms | BI-44370 ; BI44370 ; BI 44370 |
| Molecular Formula | C35H47N5O6 |
| Molecular Weight | 633.8 |
| Smile | O=C(N1CCC(N2C(NC3=CC=CC=C3CC2)=O)CC1)O[C@@H](C(N4CCC(N5CCOCC5)CC4)=O)CC6=CC(C)=C(O)C(C)=C6 |
| InChiKey | HTLWMOKBJQKDIJ-WJOKGBTCSA-N |
| InChi | InChI=1S/C35H47N5O6/c1-24-21-26(22-25(2)32(24)41)23-31(33(42)38-12-8-28(9-13-38)37-17-19-45-20-18-37)46-35(44)39-14-10-29(11-15-39)40-16-7-27-5-3-4-6-30(27)36-34(40)43/h3-6,21-22,28-29,31,41H,7-20,23H2,1-2H3,(H,36,43)/t31-/m1/s1 |
| CAS Number | 866086-05-7 |
| Related CAS | 952508-87-1 (HCl) ; 866086-05-7 (free base) ; 952508-84-8 (HBr) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | CGRP antagonist |
|---|---|
| Mechanism | CGRP receptor antagonists (Calcitonin gene-related peptide type 1 receptor antagonists) |
| Cell study | |
| Animal study | |
| Clinical study | phase II clinical trials |
Not available
Chemical Structure
