BH3I-1
Catalog No: 61402
CAS Number: 300817-68-9
Purity: 98%
BH3I-1 is an inhibitor of Bcl-xL with IC 50 of 293.95 M. BH3I-1 is a cell permeable BH3 mimetic that binds to Bcl-xL, BH3I-1 can induce cell death. BH3I-1 is a bak activator
BH3I-1 can exerted an antineoplastic effect in thyroid carcinoma cells and sensitized to sublethal concentrations of doxorubicin and bortezomib.
BH3I-1 had a strong sensitizing effect on bortezomib-induced cell death.
For research use only. We do not sell to patients.
Chemical Information
| Name | BH3I-1 |
|---|---|
| Iupac Chemical Name | BH3I-1 |
| Synonyms | BHI1; BHI-1; BHI 1; BH 3I1 |
| Molecular Formula | C15H14BrNO3S2 |
| Molecular Weight | 400.31 |
| Smile | CC(C)C(C(=O)O)N1C(=O)/C(=C\c2ccc(cc2)Br)/SC1=S |
| InChiKey | COHIEJLWRGREHV-YRNVUSSQSA-N |
| InChi | InChI=1S/C15H14BrNO3S2/c1-8(2)12(14(19)20)17-13(18)11(22-15(17)21)7-9-3-5-10(16)6-4-9/h3-8,12H,1-2H3,(H,19,20)/b11-7+ |
| CAS Number | 300817-68-9 |
| MDL | MFCD03453544 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
