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BGB-283

Catalog No: 17101620
CAS Number: 1446090-77-2;1446090-79-4
Purity: >98%

BGB-283, also known as Beigene-283 or Lifirafenib, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers.

For research use only. We do not sell to patients.

Chemical Information

NameBGB-283
SynonymsBGB-283; BGB 283; BGB283; Beigene-283; Beigene283; Beigene 283; Lifirafenib
Molecular FormulaC25H17F3N4O3
Molecular Weight478.43
Smile[H][C@@]1(C2=CC(OC3=C(CCC4=O)C(N4)=NC=C3)=CC=C2O[C@]51[H])[C@@H]5C6=NC7=CC=C(C=C7N6)C(F)(F)F
InChiKeyNGFFVZQXSRKHBM-FSSWDIPSSA-N
InChiInChI=1S/C25H17F3N4O3/c26-25(27,28)11-1-4-15-16(9-11)31-24(30-15)21-20-14-10-12(2-5-17(14)35-22(20)21)34-18-7-8-29-23-13(18)3-6-19(33)32-23/h1-2,4-5,7-10,20-22H,3,6H2,(H,30,31)(H,29,32,33)/t20-,21+,22+/m1/s1
CAS Number1446090-77-2;1446090-79-4
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid
Purity>98%
Storage3 years -20ºCpowder
SolubilitySoluble in DMSO, not in water
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17101620 - BGB-283 | CAS 1446090-77-2;1446090-79-4

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