BBT-594
Catalog No: 179133
CAS Number: 882405-89-2
Purity: 98.0%
BBT594, also known as NVP-BBT594, is potent and selective RET and JAK2 inhibitor. NVP-BBT594 impairs GDNF-RET signaling and GDNF-dependent growth of MCF7-LTED cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | BBT-594 |
|---|---|
| Iupac Chemical Name | 5-((6-acetamidopyrimidin-4-yl)oxy)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)indoline-1-carboxamide |
| Synonyms | BBT-594; BBT-594; BBT-594; NVP-BBT594; NVP BBT594; NVP BBT-594. |
| Molecular Formula | C28H30F3N7O3 |
| Molecular Weight | 569.59 |
| Smile | C(C)(=O)NC1=CC(=NC=N1)OC=1C=C2CCN(C2=CC1)C(=O)NC1=CC(=C(C=C1)CN1CCN(CC1)C)C(F)(F)F |
| InChiKey | VQLNKQZLPGLOSI-UHFFFAOYSA-N |
| InChi | InChI=1S/C28H30F3N7O3/c1-18(39)34-25-15-26(33-17-32-25)41-22-5-6-24-19(13-22)7-8-38(24)27(40)35-21-4-3-20(23(14-21)28(29,30)31)16-37-11-9-36(2)10-12-37/h3-6,13-15,17H,7-12,16H2,1-2H3,(H,35,40)(H,32,33,34,39) |
| CAS Number | 882405-89-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
