IACS-13909 is a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
For research use only. We do not sell to patients.
| Name | IACS-13909 |
|---|---|
| Iupac Chemical Name | 1-[3-(2,3-Dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-4-piperidinamine |
| Synonyms | IACS 13909 ; IACS-13909 ; IACS13909 ; |
| Molecular Formula | C17H18Cl2N6 |
| Molecular Weight | 377.27 |
| Smile | NC1(C)CCN(C2=CN=C3C(NN=C3C4=CC=CC(Cl)=C4Cl)=N2)CC1 |
| InChiKey | AMADCPJVPLUGQO-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H18Cl2N6/c1-17(20)5-7-25(8-6-17)12-9-21-15-14(23-24-16(15)22-12)10-3-2-4-11(18)13(10)19/h2-4,9H,5-8,20H2,1H3,(H,22,23,24) |
| CAS Number | 2160546-07-4 |
| Related CAS | 2160546-07-4 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white to light-yellow solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |