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Avatrombopag maleate

Catalog No.: 5141902
Cas No.: 677007-74-8
Purity : 96%

Avatrombopag maleate is an orally bioavailable, small molecule thrombopoietin receptor agonist that has been developed by Dova Pharmaceuticals for the treatment of thrombocytopenic disorders.

For research use only. We do not sell to patients.

Chemical Information

NameAvatrombopag maleate
Iupac Chemical Name4-Piperidinecarboxylic acid, 1-(3-chloro-5-(((4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1- piperazinyl)-2-thiazolyl)amino)carbonyl)-2-pyridinyl)-, (2Z)-2-butenedioate (1:1)
SynonymsAKR501 ; AKR 501 ; AKR-501 ; YM477 ; YM-477 ; YM 477 ; AS 1670542 ; AS1670542 ; AS-1670542 ; E5501 ; E-5501 ; E 5501;
Molecular FormulaC33H38Cl2N6O7S2
Molecular Weight765.73
SmileO=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.O=C(O)/C=C/C(O)=O
InChiKeyMISPBGHDNZYFNM-WLHGVMLRSA-N
InChiInChI=1S/C29H34Cl2N6O3S2.C4H4O4/c30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40;5-3(6)1-2-4(7)8/h14-18,21H,1-13H2,(H,39,40)(H,33,34,38);1-2H,(H,5,6)(H,7,8)/b;2-1+
CAS Number677007-74-8
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Ordering Information

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FormulationOff-white solid to white solid
Purity96%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

5141902 - Avatrombopag maleate | CAS 677007-74-8

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