Atumelnant ( CRN-04894 )
Catalog No: 26A004
CAS Number: 2392970-97-5
Purity: ≧98.0%
Atumelnant ( CRN-04894 ) is the first investigational once-daily, oral melanocortin type 2 receptor (MC2R) receptor antagonist that selectively blocks the activity of ACTH at the adrenal gland.
For research use only. We do not sell to patients.
Chemical Information
| Name | Atumelnant ( CRN-04894 ) |
|---|---|
| Iupac Chemical Name | N-[(3S)-1-Azabicyclo[2.2.2]octan-3-yl]-6-(2-ethoxyphenyl)-3-[(2R)-2-ethyl-4-[1-(trifluoromethyl)cyclobutane-1-carbonyl]piperazin-1-yl]pyridine-2-carboxamide |
| Synonyms | Atumelnant ; CRN-04894 ; CRN04894 ; CRN 04894 |
| Molecular Formula | C33H42F3N5O3 |
| Molecular Weight | 613.32 |
| Smile | O=C(C1=NC(C2=CC=CC=C2OCC)=CC=C1N3[C@H](CC)CN(C(C4(C(F)(F)F)CCC4)=O)CC3)N[C@@H]5CN6CCC5CC6 |
| InChiKey | QJRFBKYETDVAJQ-ZEQKJWHPSA-N |
| InChi | InChI=1S/C33H42F3N5O3/c1-3-23-20-40(31(43)32(14-7-15-32)33(34,35)36)18-19-41(23)27-11-10-25(24-8-5-6-9-28(24)44-4-2)37-29(27)30(42)38-26-21-39-16-12-22(26)13-17-39/h5-6,8-11,22-23,26H,3-4,7,12-21H2,1-2H3,(H,38,42)/t23-,26-/m1/s1 |
| CAS Number | 2392970-97-5 |
| Related CAS | 2392970-97-5 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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