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Alda 1 Catalog No : 102702

Chemical Information

Product NameAlda 1
Iupac Chemical NameN-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide 
SynonymsALDH2 Agonist 
Molecular FormulaC15H11Cl2NO3 
Molecular Weight324.159 
SmileO1COC2=C1C=CC(=C2)CNC(C2=C(C=CC=C2Cl)Cl)=O
InChiKeyNMKJFZCBCIUYHI-UHFFFAOYSA-N
InChiInChI=1S/C15H11Cl2NO3/c16-10-2-1-3-11(17)14(10)15(19)18-7-9-4-5-12-13(6-9)21-8-20-12/h1-6H,7-8H2,(H,18,19)
Cas349438-38-6

Technical Data

AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
Quality control

Description

Alda 1 is a cell-permeable benzamide compound that selectively enhances the activity of both the wild-type ALDH2*1 and the east asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (2.1-, 2.2, and 11-fold activation of 20 g wt homo, wt/mut hetero, and mut homo tetramer, respectively, at 100 M), while exhibiting no effect toward alcohol dehydrogenase 1, cytosolic ALDH1, or mitochondrial ALDH5. 

Chemical Structure

102702 - Alda 1 | CAS 349438-38-6

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